(An Auto-immune disease)
What is rheumatoid arthritis?
Rheumatoid arthritis is one type of an autoimmune disease which may occur due to the body’s immune system will damage the joint tissue, leads to causing swelling of the joint lining
One person affected by rheumatoid arthritis, it gets spreads throughout the body, it may also be known as osteoarthritis.
RA classified as:
There are various types of RA involved, some of the following
Seropositive RA: +ve rheumatoid factor
Seronegative RA: -ve rheumatoid factor, -ve anti-CCP test
Juvenile idiopathic arthritis (JIV): occurs at the age of younger than 17 years of age.
A symptom appears in RA:
RA is a chronic syndrome, may cause serious effects
The major symptoms of RA is inflammation and worsening pain in joints
Most common symptoms like;
Lack of joint function, fever, loss of weight, fatigue
In some people RA may causes adverse effect in non-joint structures like;
Skin, eyes, lungs, heart, kidneys, salivary glands, nerve tissues, bone marrow, blood vessels.
Causes of RA:
In genetic factor: Genes has vital role in immune system, some genetic factor involved in route cause for rheumatoid arthritis
In environmental factors: Some of the infection may generate RA in body due to environmental conditions
RA developed when the immune system will disrupt the synovium, lining of membrane which is surrounded the joints
This result as inflammation occurs, causes thickening of synovium and damage the cartilage & bone which are present within the joint. Thus the tendons will become weak and stretch
Finally joints will drops its alignment & shapes.
The circumstances which will increase the risk of rheumatoid arthritis includes as;
Sex: women has more chance to get RA than men
Age: RA arise in any age, frequently it occur at the age between 40 to 60 years
Family history: RA is also a genetic disorder, if a family member has suffered with RA, have increased chance
Other factors like smoking, obesity, environmental hazard.
What are the complications occur while getting RA:
Dry eye and mouth
Carpel tunnel syndrome
Atypical body balance
Methods used to analyze and diagnose RA
Rheumatoid arthritis test
Anti-citrullinated protein antibody test (anti-CCP)
Anti-nuclear antibody test
C-reactive protein test
Erythrocyte sedimentation test.
How to treat RA:
Rheumatoid arthritis is non-curable disease, but it can prevent and helps to dominate the pain
Some of the medications involved in the treatment of RA include;
Drugs used to reduce the pain & swelling
NSAIDS (non-steroidal anti-inflammatory drugs)
Drugs used to passive the damage that RA origin to the body
Disease-modifying anti-rheumatoid drugs
Janus Kinase (JAK) inhibitors